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Suspected causes of Chest Pain

 
 
Skin and subcutaneous lesions [including adiposis dolorosa, thrombophlebitis of thoracoepigastric vein (Mondor disease)]
Breast lesions
  • Fibroadenosis
  • Chronic cystic mastitis
  • Acute breast abscess or mastitis
  • Carcinoma
  • Trauma and hematoma
Musculoskeletal disorders
  • Bruised or fractured rib
  • Periostitis
  • Periosteal hematoma
  • Costochondritis (Tietze syndrome)
  • Slipping costal cartilage
  • Intercostal muscle “stitchâ€‌ or cramp
  • Intercostal myositis
  • Pectoral or other muscular strain
  • Shoulder girdle disorders (e.g., subacromial bursitis)
  • Cervical disc herniation
  • Dorsal spine osteoarthritis
  • Thoracic outlet syndrome
  • Fibromyalgia

Neuralgia
  • Herpes zoster
  • Tabes dorsalis
  • Neurofibroma
  • Neoplasm
Pericardial disease
  • Pericarditis
  • Neoplasm
  • Congenital absence of left pericardium
Mediastinal disease
  • Mediastinal emphysema
  • Neoplasm
  • Mediastinitis
Cardiovascular disease
  • Coronary heart diseases
    • Acute coronary syndrome
    • Acute myocardial infarction
    • Angina pectoris
  • Aortic valvular disease
  • Hypertrophic cardiomyopathy
  • Cardiomyopathy
  • Mitral valve prolapse
  • Acute aortic dissection
  • Thoracic aortic aneurysm
  • Myocarditis
  • Cardiac rupture
  • Ruptured sinus of Valsalva aneurysm
Pleural or pulmonary disease
  • Pleuritis of any etiology (e.g., pneumothorax)
  • Tracheobronchitis
  • Pneumonia
  • Pulmonary hypertension
  • Pulmonary thromboembolism
  • Pulmonary artery rupture
  • Neoplasm
    • Bronchogenic carcinoma
    • Metastatic tumor
    • Mesothelioma
    • Other parenchymal lesions
Gastrointestinal disease
  • Esophageal lesions
    • Esophagitis
    • Esophageal spasm
    • Mallory-Weiss syndrome
    • Esophageal rupture
    • Foreign body
    • Carcinoma
    • Zenker diverticulum
    • Plummer-Vinson syndrome
    • Hyperalgesia
Peptic ulcer disease (with or without perforation)
Gastric distention
Gastritis
  • Biliary disease
  • Acute cholecystitis
  • Biliary colic
Distention of the liver
  • Pancreatitis
  • Subphrenic abscess
  • Splenic infarct
  • Splenic flexure syndrome
Thyroiditis
Psychogenic causes
  • Hyperventilation
  • Anxiety-panic disorders
  • Depression
  • Somatization disorders
 
 
References
1. Braunwald E. Examination of the patient. See Bibliography, 5.
2. Simel DL. Approach to the patient: history and physical examination. See Bibliography, 2.
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